Resetting audio interface settings
Yesterday, during a stream, Drambo kept resetting my Zoom AMS-24 audio interface settings from 48 kHz to 44.1 kHz. At the same time, the Pro Q-3 equalizers loaded on the tracks would crash. When I reopened the project, it happened again a few minutes later.
What could be the problem?

Comments
Drambo doesn't change audio settings, audio interface it initialized once on start. Was there another audio app running in the background?
Siri has a tendency to mess with the sample-rates so be sure it's completely disabled...
It looks like the problem is with the USB hub. All my hubs had an HDMI port. The other day, I connected a hub without HDMI and didn't notice any dropouts. Moreover, I can freely change the sampling rate, which I couldn't before.
@ptrvch - interesting find!
I'm definitely going to take note of that as a possibility when others report similar problems. Such issues come up fairly often regardless of the host being used.